Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans

Elevated nonfasting TG-rich lipoprotein levels are a risk factor for CVD. To further evaluate the relevance of LDL-receptor (LDLr) pathway and heparan sulfate proteoglycans (HSPGs) in TG homeostasis, we analyzed fasting and postprandial TG levels in mice bearing combined heterozygous mutations in bo...

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Detaylı Bibliyografya
Yayımlandı:J Lipid Res
Asıl Yazarlar: Mooij, Hans L., Bernelot Moens, Sophie J., Gordts, Philip L. S. M., Stanford, Kristin I., Foley, Erin M., van den Boogert, Marjolein A. W., Witjes, Julia J., Hassing, H. Carlijne, Tanck, Michael W., van de Sande, Michiel A. J., Levels, J. Han, Kastelein, John J. P., Stroes, Erik S. G., Dallinga-Thie, Geesje M., Esko, Jeff D., Nieuwdorp, Max
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2015
Konular:
Patient-Oriented and Epidemiological Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340313/
https://ncbi.nlm.nih.gov/pubmed/25568062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M053504
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