Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans

Elevated nonfasting TG-rich lipoprotein levels are a risk factor for CVD. To further evaluate the relevance of LDL-receptor (LDLr) pathway and heparan sulfate proteoglycans (HSPGs) in TG homeostasis, we analyzed fasting and postprandial TG levels in mice bearing combined heterozygous mutations in bo...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Mooij, Hans L., Bernelot Moens, Sophie J., Gordts, Philip L. S. M., Stanford, Kristin I., Foley, Erin M., van den Boogert, Marjolein A. W., Witjes, Julia J., Hassing, H. Carlijne, Tanck, Michael W., van de Sande, Michiel A. J., Levels, J. Han, Kastelein, John J. P., Stroes, Erik S. G., Dallinga-Thie, Geesje M., Esko, Jeff D., Nieuwdorp, Max
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Patient-Oriented and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340313/
https://ncbi.nlm.nih.gov/pubmed/25568062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M053504
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