SULF2 Strongly Prediposes to Fasting and Postprandial Triglycerides in Patients with Obesity and Type 2 Diabetes Mellitus

OBJECTIVE: Hepatic overexpression of sulfatase-2 (SULF2), a heparan sulfate remodelling enzyme, strongly contributes to high triglyceride (TG) levels in obese, type 2 diabetic (T2DM) db/db mice. Nevertheless, data in humans are lacking. Here we sought to investigate the association of human hepatic...

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Main Authors: Hassing, H. Carlijne, Surendran, R. Preethi, Derudas, Bruno, Verrijken, An, Francque, Sven M., Mooij, Hans L., Bernelot Moens, Sophie J., ’t Hart, Leen M., Nijpels, Giel, Dekker, Jacqueline M., Williams, Kevin Jon, Stroes, Erik S. G., Van Gaal, Luc F., Staels, Bart, Nieuwdorp, Max, Dallinga-Thie, Geesje M.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008695/
https://ncbi.nlm.nih.gov/pubmed/24339435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.20682
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