Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans

Elevated nonfasting TG-rich lipoprotein levels are a risk factor for CVD. To further evaluate the relevance of LDL-receptor (LDLr) pathway and heparan sulfate proteoglycans (HSPGs) in TG homeostasis, we analyzed fasting and postprandial TG levels in mice bearing combined heterozygous mutations in bo...

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Dades bibliogràfiques
Publicat a:J Lipid Res
Autors principals: Mooij, Hans L., Bernelot Moens, Sophie J., Gordts, Philip L. S. M., Stanford, Kristin I., Foley, Erin M., van den Boogert, Marjolein A. W., Witjes, Julia J., Hassing, H. Carlijne, Tanck, Michael W., van de Sande, Michiel A. J., Levels, J. Han, Kastelein, John J. P., Stroes, Erik S. G., Dallinga-Thie, Geesje M., Esko, Jeff D., Nieuwdorp, Max
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2015
Matèries:
Patient-Oriented and Epidemiological Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340313/
https://ncbi.nlm.nih.gov/pubmed/25568062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M053504
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