ABCB4 exports phosphatidylcholine in a sphingomyelin-dependent manner

ABCB4, which is specifically expressed on the canalicular membrane of hepatocytes, exports phosphatidylcholine (PC) into bile. Because SM depletion increases cellular PC content and stimulates PC and cholesterol efflux by ABCA1, a key transporter involved in generation of HDL, we predicted that SM d...

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Bibliografische gegevens
Gepubliceerd in:J Lipid Res
Hoofdauteurs: Zhao, Yu, Ishigami, Masato, Nagao, Kohjiro, Hanada, Kentaro, Kono, Nozomu, Arai, Hiroyuki, Matsuo, Michinori, Kioka, Noriyuki, Ueda, Kazumitsu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2015
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340311/
https://ncbi.nlm.nih.gov/pubmed/25601960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M056622
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