Inhibiting p38 mitogen-activated protein kinase attenuates cerebral ischemic injury in Swedish mutant amyloid precursor protein transgenic mice☆

Cerebral ischemia was induced using photothrombosis 1 hour after intraperitoneal injection of the p38 mitogen-activated protein kinase (MAPK) inhibitor SB239063 into Swedish mutant amyloid precursor protein (APP/SWE) transgenic and non-transgenic mice. The number of surviving neurons in the penumbra...

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Detalles Bibliográficos
Publicado en:Neural Regen Res
Main Authors: Zou, Liangyu, Qin, Haiyan, He, Yitao, Huang, Heming, Lu, Yi, Chu, Xiaofan
Formato: Artigo
Idioma:Inglês
Publicado: Medknow Publications & Media Pvt Ltd 2012
Assuntos:
Research and Report: Neurodegenerative Disease and Neural Regeneration
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340022/
https://ncbi.nlm.nih.gov/pubmed/25722699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-5374.2012.14.007
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