Increased Susceptibility to Ischemic Brain Damage in Transgenic Mice Overexpressing the Amyloid Precursor Protein

We studied the role of the amyloid precursor protein (APP) in ischemic brain damage using transgenic mice overexpressing APP. The middle cerebral artery (MCA) was occluded in FVB/N mice expressing APP(695).SWE (Swedish mutation) and in nontransgenic littermates. Infarct volume (cubic millimeters) wa...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Zhang, Fangyi, Eckman, Chris, Younkin, Steven, Hsiao, Karen K., Iadecola, Costantino
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 1997
Assuntos:
Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793926/
https://ncbi.nlm.nih.gov/pubmed/9315887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-20-07655.1997
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares