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Identifying restrictions in the order of accumulation of mutations during tumor progression: effects of passengers, evolutionary models, and sampling
BACKGROUND: Cancer progression is caused by the sequential accumulation of mutations, but not all orders of accumulation are equally likely. When the fixation of some mutations depends on the presence of previous ones, identifying restrictions in the order of accumulation of mutations can lead to th...
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| Gepubliceerd in: | BMC Bioinformatics |
|---|---|
| Hoofdauteur: | |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4339747/ https://ncbi.nlm.nih.gov/pubmed/25879190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0466-7 |
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