Effects of Inducers and Epoxide Hydrase on the Metabolism of Benzo[a]pyrene by Liver Microsomes and a Reconstituted System: Analysis by High Pressure Liquid Chromatography

The mobilities of 24 potential metabolites of benzo[a]pyrene were examined with high pressure liquid chromatography. Twelve phenols, five quinones, four dihydrodiols, and three oxides were studied. The chromatographic procedure employed allowed the separation and quantitation of benzopyrene metaboli...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Holder, Gerald, Yagi, Haruhiko, Dansette, Patrick, Jerina, Donald M., Levin, W., Lu, Anthony Y. H., Conney, A. H.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1974
Sujets:	Biological Sciences: Biochemistry
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433882/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4530987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.11.4356
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