Mutagenic and cytotoxic activity of benzol[a]pyrene 4,5-, 7,8-, and 9,10-oxides and the six corresponding phenols.

The benzo[a]pyrene 4,5-, 7,8-, and 9,10-oxides and the six corresponding phenols (4-, 5-, 7-, 8-, 9-, and 10-hydroxybenzo[a]pyrene) have been tested for mutagenic and cytotoxic activity in bacteria and in a mammalian cell culture system. Benzo[a]pyrene 4,5-oxide (K-region) was highly mutagenic in tw...

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Detalhes bibliográficos
Main Authors: Wood, A W, Goode, R L, Chang, R L, Levin, W, Conney, A H, Yagi, H, Dansette, P M, Jerina, D M
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC432944/
https://ncbi.nlm.nih.gov/pubmed/1103140
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