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Effects of Inducers and Epoxide Hydrase on the Metabolism of Benzo[a]pyrene by Liver Microsomes and a Reconstituted System: Analysis by High Pressure Liquid Chromatography

The mobilities of 24 potential metabolites of benzo[a]pyrene were examined with high pressure liquid chromatography. Twelve phenols, five quinones, four dihydrodiols, and three oxides were studied. The chromatographic procedure employed allowed the separation and quantitation of benzopyrene metaboli...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Proc Natl Acad Sci U S A
المؤلفون الرئيسيون: Holder, Gerald, Yagi, Haruhiko, Dansette, Patrick, Jerina, Donald M., Levin, W., Lu, Anthony Y. H., Conney, A. H.
التنسيق: Artigo
اللغة:Inglês
منشور في: National Academy of Sciences 1974
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433882/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4530987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.11.4356
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