Effects of Inducers and Epoxide Hydrase on the Metabolism of Benzo[a]pyrene by Liver Microsomes and a Reconstituted System: Analysis by High Pressure Liquid Chromatography

The mobilities of 24 potential metabolites of benzo[a]pyrene were examined with high pressure liquid chromatography. Twelve phenols, five quinones, four dihydrodiols, and three oxides were studied. The chromatographic procedure employed allowed the separation and quantitation of benzopyrene metaboli...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Holder, Gerald, Yagi, Haruhiko, Dansette, Patrick, Jerina, Donald M., Levin, W., Lu, Anthony Y. H., Conney, A. H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1974
Assuntos:	Biological Sciences: Biochemistry
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433882/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4530987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.11.4356
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