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Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number
BACKGROUND: The borders of Thailand harbour the world’s most multidrug resistant Plasmodium falciparum parasites. In 1984 mefloquine was introduced as treatment for uncomplicated falciparum malaria, but substantial resistance developed within 6 years. A combination of artesunate with mefloquine now...
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Publicado no: | Lancet |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4337987/ https://ncbi.nlm.nih.gov/pubmed/15288742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(04)16767-6 |
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