Intrahost Selection of Plasmodium falciparum pfmdr1 Alleles after Antimalarial Treatment on the Northwestern Border of Thailand

BACKGROUND: Increased pfmdr1 copy number is associated with reduced susceptibility to structurally unrelated antimalarial drugs. We assessed how administration of different antimalarial drugs altered pfmdr1 polymorphism in parasites from patients who experienced treatment failure. METHODS: In studie...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Uhlemann, Anne-Catrin, McGready, Rose, Ashley, Elizabeth A., Brockman, Alan, Singhasivanon, Pratap, Krishna, Sanjeev, White, Nicholas J., Nosten, François, Price, Ric N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337981/
https://ncbi.nlm.nih.gov/pubmed/17152017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/509809
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