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Intrahost Selection of Plasmodium falciparum pfmdr1 Alleles after Antimalarial Treatment on the Northwestern Border of Thailand

BACKGROUND: Increased pfmdr1 copy number is associated with reduced susceptibility to structurally unrelated antimalarial drugs. We assessed how administration of different antimalarial drugs altered pfmdr1 polymorphism in parasites from patients who experienced treatment failure. METHODS: In studie...

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Détails bibliographiques
Publié dans:J Infect Dis
Auteurs principaux: Uhlemann, Anne-Catrin, McGready, Rose, Ashley, Elizabeth A., Brockman, Alan, Singhasivanon, Pratap, Krishna, Sanjeev, White, Nicholas J., Nosten, François, Price, Ric N.
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337981/
https://ncbi.nlm.nih.gov/pubmed/17152017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/509809
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