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Decreasing pfmdr1 Copy Number Suggests that Plasmodium falciparum in Western Cambodia Is Regaining In Vitro Susceptibility to Mefloquine

Dihydroartemisinin-piperaquine is the current frontline artemisinin combination therapy (ACT) for Plasmodium falciparum malaria in Cambodia but is now failing in several western provinces. To investigate artesunate plus mefloquine (AS+MQ) as a replacement ACT, we measured the prevalence of multiple...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Lim, Pharath, Dek, Dalin, Try, Vorleak, Sreng, Sokunthea, Suon, Seila, Fairhurst, Rick M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394809/
https://ncbi.nlm.nih.gov/pubmed/25712365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05163-14
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