Plasmodium falciparum pfmdr1 Amplification, Mefloquine Resistance, and Parasite Fitness

Mefloquine is widely used in combination with artemisinin derivatives for the treatment of falciparum malaria. Mefloquine resistance in Plasmodium falciparum has been related to increased copy numbers of multidrug-resistant gene 1 (pfmdr1). We studied the ex vivo dynamics of pfmdr1 gene amplificatio...

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Bibliografiset tiedot
Päätekijät: Preechapornkul, Piyanuch, Imwong, Mallika, Chotivanich, Kesinee, Pongtavornpinyo, Wirichada, Dondorp, Arjen M., Day, Nicholas P. J., White, Nicholas J., Pukrittayakamee, Sasithon
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2009
Aiheet:
Mechanisms of Resistance
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663078/
https://ncbi.nlm.nih.gov/pubmed/19164150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00241-08
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