Plasmodium falciparum pfmdr1 Amplification, Mefloquine Resistance, and Parasite Fitness

Mefloquine is widely used in combination with artemisinin derivatives for the treatment of falciparum malaria. Mefloquine resistance in Plasmodium falciparum has been related to increased copy numbers of multidrug-resistant gene 1 (pfmdr1). We studied the ex vivo dynamics of pfmdr1 gene amplificatio...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Preechapornkul, Piyanuch, Imwong, Mallika, Chotivanich, Kesinee, Pongtavornpinyo, Wirichada, Dondorp, Arjen M., Day, Nicholas P. J., White, Nicholas J., Pukrittayakamee, Sasithon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Mechanisms of Resistance
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663078/
https://ncbi.nlm.nih.gov/pubmed/19164150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00241-08
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