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Notch inhibits chondrogenic differentiation of mesenchymal progenitor cells by targeting Twist1
While Notch signaling plays a critical role in the regulation of cartilage formation, its downstream targets are unknown. To address this we performed gain and losses of function experiments and demonstrate that Notch inhibition of chondrogenesis acts via up-regulation of the transcription factor Tw...
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| Publicado no: | Mol Cell Endocrinol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4337804/ https://ncbi.nlm.nih.gov/pubmed/25596548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.01.015 |
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