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Notch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest

Cell cycle regulation is critical for chondrocyte differentiation and hypertrophy. Recently we identified the Notch signaling pathway as an important regulator of chondrocyte proliferation and differentiation during mouse cartilage development. To investigate the underlying mechanisms, we assessed t...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Shang, Xifu, Wang, Jinwu, Luo, Zhengliang, Wang, Yongjun, Morandi, Massimo M., Marymont, John V., Hilton, Matthew J., Dong, Yufeng
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857138/
https://ncbi.nlm.nih.gov/pubmed/27146698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25594
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