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Notch inhibits chondrogenic differentiation of mesenchymal progenitor cells by targeting Twist1

While Notch signaling plays a critical role in the regulation of cartilage formation, its downstream targets are unknown. To address this we performed gain and losses of function experiments and demonstrate that Notch inhibition of chondrogenesis acts via up-regulation of the transcription factor Tw...

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Podrobná bibliografie
Vydáno v:Mol Cell Endocrinol
Hlavní autoři: Tian, Ye, Xu, Ying, Fu, Qin, Chang, Martin, Wang, Yongjun, Shang, Xifu, Wan, Chao, Marymont, John V., Dong, Yufeng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337804/
https://ncbi.nlm.nih.gov/pubmed/25596548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.01.015
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