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Notch inhibits chondrogenic differentiation of mesenchymal progenitor cells by targeting Twist1

While Notch signaling plays a critical role in the regulation of cartilage formation, its downstream targets are unknown. To address this we performed gain and losses of function experiments and demonstrate that Notch inhibition of chondrogenesis acts via up-regulation of the transcription factor Tw...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cell Endocrinol
Päätekijät: Tian, Ye, Xu, Ying, Fu, Qin, Chang, Martin, Wang, Yongjun, Shang, Xifu, Wan, Chao, Marymont, John V., Dong, Yufeng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337804/
https://ncbi.nlm.nih.gov/pubmed/25596548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.01.015
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