Transient gamma-secretase inhibition accelerates and enhances fracture repair likely via Notch signaling modulation

Approximately 10% of skeletal fractures result in healing complications and non-union, while most fractures repair with appropriate stabilization and without pharmacologic intervention. It is the latter injuries that cannot be underestimated as the expenses associated with their treatment and subseq...

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Bibliographic Details
Published in:Bone
Main Authors: Wang, Cuicui, Shen, Jie, Yukata, Kiminori, Inzana, Jason A., O'Keefe, Regis J., Awad, Hani A., Hilton, Matthew J.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336841/
https://ncbi.nlm.nih.gov/pubmed/25527421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.12.007
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