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In Vitro Resistance Studies with Bacteria That Exhibit Low Mutation Frequencies: Prediction of “Antimutant” Linezolid Concentrations Using a Mixed Inoculum Containing both Susceptible and Resistant Staphylococcus aureus

Bacterial resistance studies using in vitro dynamic models are highly dependent on the starting inoculum that might or might not contain spontaneously resistant mutants (RMs). To delineate concentration-resistance relationships with linezolid-exposed Staphylococcus aureus, a mixed inoculum containin...

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發表在:Antimicrob Agents Chemother
Main Authors: Firsov, Alexander A., Golikova, Maria V., Strukova, Elena N., Portnoy, Yury A., Romanov, Andrey V., Edelstein, Mikhail V., Zinner, Stephen H.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335834/
https://ncbi.nlm.nih.gov/pubmed/25451050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04214-14
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