Searching for the Optimal Predictor of Ciprofloxacin Resistance in Klebsiella pneumoniae by Using In Vitro Dynamic Models

There is growing evidence of applicability of the hypothesis of the mutant selection window (MSW), i.e., the range between the MIC and the mutant prevention concentration (MPC), within which the enrichment of resistant mutants is most probable. However, it is not clear if MPC-based pharmacokinetic v...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Strukova, Elena N., Portnoy, Yury A., Romanov, Andrey V., Edelstein, Mikhail V., Zinner, Stephen H., Firsov, Alexander A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775939/
https://ncbi.nlm.nih.gov/pubmed/26643328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02334-15
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