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Comparative Pharmacodynamics and Antimutant Potentials of Doripenem and Imipenem with Ciprofloxacin-Resistant Pseudomonas aeruginosa in an In Vitro Model

To compare the antipseudomonal efficacy of doripenem and imipenem as well as their abilities to restrict the enrichment of resistant Pseudomonas aeruginosa, multiple-dosing regimens of each drug were simulated at comparable values of the cumulative percentages of a 24-h period that the drug concentr...

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Detalhes bibliográficos
Main Authors: Firsov, Alexander A., Gilbert, Deborah, Greer, Kenneth, Portnoy, Yury A., Zinner, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294888/
https://ncbi.nlm.nih.gov/pubmed/22203591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05964-11
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