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Comparative Pharmacodynamics and Antimutant Potentials of Doripenem and Imipenem with Ciprofloxacin-Resistant Pseudomonas aeruginosa in an In Vitro Model

To compare the antipseudomonal efficacy of doripenem and imipenem as well as their abilities to restrict the enrichment of resistant Pseudomonas aeruginosa, multiple-dosing regimens of each drug were simulated at comparable values of the cumulative percentages of a 24-h period that the drug concentr...

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Détails bibliographiques
Auteurs principaux: Firsov, Alexander A., Gilbert, Deborah, Greer, Kenneth, Portnoy, Yury A., Zinner, Stephen H.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294888/
https://ncbi.nlm.nih.gov/pubmed/22203591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05964-11
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