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Comparative Pharmacodynamics and Antimutant Potentials of Doripenem and Imipenem with Ciprofloxacin-Resistant Pseudomonas aeruginosa in an In Vitro Model

To compare the antipseudomonal efficacy of doripenem and imipenem as well as their abilities to restrict the enrichment of resistant Pseudomonas aeruginosa, multiple-dosing regimens of each drug were simulated at comparable values of the cumulative percentages of a 24-h period that the drug concentr...

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Bibliografische gegevens
Hoofdauteurs: Firsov, Alexander A., Gilbert, Deborah, Greer, Kenneth, Portnoy, Yury A., Zinner, Stephen H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294888/
https://ncbi.nlm.nih.gov/pubmed/22203591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05964-11
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