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Prediction of the Effects of Inoculum Size on the Antimicrobial Action of Trovafloxacin and Ciprofloxacin against Staphylococcus aureus and Escherichia coli in an In Vitro Dynamic Model

The effect of inoculum size (N(0)) on antimicrobial action has not been extensively studied in in vitro dynamic models. To investigate this effect and its predictability, killing and regrowth kinetics of Staphylococcus aureus and Escherichia coli exposed to monoexponentially decreasing concentration...

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Detalhes bibliográficos
Main Authors: Firsov, Alexander A., Vostrov, Sergey N., Kononenko, Olga V., Zinner, Stephen H., Portnoy, Yury A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89150/
https://ncbi.nlm.nih.gov/pubmed/10049257
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