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Relationships of the Area under the Curve/MIC Ratio to Different Integral Endpoints of the Antimicrobial Effect: Gemifloxacin Pharmacodynamics in an In Vitro Dynamic Model

Most integral endpoints of the antimicrobial effect are determined over an arbitrarily chosen time period, such as the dosing interval (τ), regardless of the actual effect duration. Unlike the τ-related endpoints, the intensity of the antimicrobial effect (I(E)) does consider its duration—from time...

詳細記述

保存先:
書誌詳細
主要な著者: Firsov, Alexander A., Lubenko, Irene Y., Portnoy, Yury A., Zinner, Stephen H., Vostrov, Sergey N.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC90395/
https://ncbi.nlm.nih.gov/pubmed/11181382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.927-931.2001
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