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Relationships of the Area under the Curve/MIC Ratio to Different Integral Endpoints of the Antimicrobial Effect: Gemifloxacin Pharmacodynamics in an In Vitro Dynamic Model

Most integral endpoints of the antimicrobial effect are determined over an arbitrarily chosen time period, such as the dosing interval (τ), regardless of the actual effect duration. Unlike the τ-related endpoints, the intensity of the antimicrobial effect (I(E)) does consider its duration—from time...

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Publicado no:Antimicrob Agents Chemother
Principais autores: Firsov, Alexander A., Lubenko, Irene Y., Portnoy, Yury A., Zinner, Stephen H., Vostrov, Sergey N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90395/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11181382/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.3.927-931.2001
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