Prediction of the Effects of Inoculum Size on the Antimicrobial Action of Trovafloxacin and Ciprofloxacin against Staphylococcus aureus and Escherichia coli in an In Vitro Dynamic Model

The effect of inoculum size (N(0)) on antimicrobial action has not been extensively studied in in vitro dynamic models. To investigate this effect and its predictability, killing and regrowth kinetics of Staphylococcus aureus and Escherichia coli exposed to monoexponentially decreasing concentration...

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Bibliographic Details
Main Authors: Firsov, Alexander A., Vostrov, Sergey N., Kononenko, Olga V., Zinner, Stephen H., Portnoy, Yury A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC89150/
https://ncbi.nlm.nih.gov/pubmed/10049257
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