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Prevalence and Gene Characteristics of Antibodies with Cofactor-induced HIV-1 Specificity
The healthy immune repertoire contains a fraction of antibodies that bind to various biologically relevant cofactors, including heme. Interaction of heme with some antibodies results in induction of new antigen binding specificities and acquisition of binding polyreactivity. In vivo, extracellular h...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335253/ https://ncbi.nlm.nih.gov/pubmed/25564611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.618124 |
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