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Impact of Antigen Density on the Binding Mechanism of IgG Antibodies

The density and distribution pattern of epitopes at the surface of pathogens have a profound impact on immune responses. Although multiple lines of evidence highlight the significance of antigen surface density for antibody binding, a quantitative description of its effect on recognition mechanisms...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Hadzhieva, Maya, Pashov, Anastas D., Kaveri, Srinivas, Lacroix-Desmazes, Sébastien, Mouquet, Hugo, Dimitrov, Jordan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476644/
https://ncbi.nlm.nih.gov/pubmed/28630473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03942-z
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