Prevalence and Gene Characteristics of Antibodies with Cofactor-induced HIV-1 Specificity

The healthy immune repertoire contains a fraction of antibodies that bind to various biologically relevant cofactors, including heme. Interaction of heme with some antibodies results in induction of new antigen binding specificities and acquisition of binding polyreactivity. In vivo, extracellular h...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lecerf, Maxime, Scheel, Tobias, Pashov, Anastas D., Jarossay, Annaelle, Ohayon, Delphine, Planchais, Cyril, Mesnage, Stephane, Berek, Claudia, Kaveri, Srinivas V., Lacroix-Desmazes, Sébastien, Dimitrov, Jordan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335253/
https://ncbi.nlm.nih.gov/pubmed/25564611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.618124
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