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Molecular Pathways: The PERKs and Pitfalls of Targeting the Unfolded Protein Response in Cancer
The endoplasmic reticulum (ER) is a highly specialized organelle that provides an oxidizing, pro-folding environment for protein synthesis and maturation. The ER also hosts a dynamic signaling network that can sense and respond to physiological changes that impact its environment, thereby influencin...
Gardado en:
| Publicado en: | Clin Cancer Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4334714/ https://ncbi.nlm.nih.gov/pubmed/25182515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3239 |
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