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Generation and characterization of an analog-sensitive PERK allele
Restriction of nutrients and oxygen in the tumor microenvironment disrupts ER homeostasis and adaptation to such stress is mediated by the key UPR effector PERK. Given its pro-tumorigenic activity, significant efforts have been made to elucidate the molecular mechanisms that underlie PERK function....
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119078/ https://ncbi.nlm.nih.gov/pubmed/24846185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.29274 |
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