CNPY2 is a Key Initiator of the PERK-CHOP Pathway of the Unfolded Protein Response

The unfolded protein response (UPR) in the endoplasmic reticulum (ER) is a highly conserved protein quality control mechanism critical for cells to make survival-or-death decisions under ER stress conditions. However, how UPR sensors are activated remains unclear. Here, we report that ER luminal pro...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Hong, Feng, Liu, Bei, Wu, Bill X, Morrell, Jordan, Roth, Brady, Davies, Christopher, Sun, Shaoli, Diehl, J. Alan, Li, Zihai
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102046/
https://ncbi.nlm.nih.gov/pubmed/28869608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3458
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