Identification of Novel Potential Antibiotics against Staphylococcus Using Structure-Based Drug Screening Targeting Dihydrofolate Reductase

[Image: see text] The emergence of multidrug-resistant Staphylococcus aureus (S. aureus) makes the treatment of infectious diseases in hospitals more difficult and increases the mortality of the patients. In this study, we attempted to identify novel potent antibiotic candidate compounds against S....

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Bibliografske podrobnosti
izdano v:J Chem Inf Model
Main Authors: Kobayashi, Maiko, Kinjo, Tomohiro, Koseki, Yuji, Bourne, Christina R., Barrow, William W., Aoki, Shunsuke
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334291/
https://ncbi.nlm.nih.gov/pubmed/24655350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci400686d
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