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Identification of Novel Potential Antibiotics against Staphylococcus Using Structure-Based Drug Screening Targeting Dihydrofolate Reductase

[Image: see text] The emergence of multidrug-resistant Staphylococcus aureus (S. aureus) makes the treatment of infectious diseases in hospitals more difficult and increases the mortality of the patients. In this study, we attempted to identify novel potent antibiotic candidate compounds against S....

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Detalhes bibliográficos
Publicado no:J Chem Inf Model
Main Authors: Kobayashi, Maiko, Kinjo, Tomohiro, Koseki, Yuji, Bourne, Christina R., Barrow, William W., Aoki, Shunsuke
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334291/
https://ncbi.nlm.nih.gov/pubmed/24655350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci400686d
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