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Identification of Novel Potential Antibiotics against Staphylococcus Using Structure-Based Drug Screening Targeting Dihydrofolate Reductase

[Image: see text] The emergence of multidrug-resistant Staphylococcus aureus (S. aureus) makes the treatment of infectious diseases in hospitals more difficult and increases the mortality of the patients. In this study, we attempted to identify novel potent antibiotic candidate compounds against S....

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Publicado en:J Chem Inf Model
Autores principales: Kobayashi, Maiko, Kinjo, Tomohiro, Koseki, Yuji, Bourne, Christina R., Barrow, William W., Aoki, Shunsuke
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334291/
https://ncbi.nlm.nih.gov/pubmed/24655350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci400686d
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