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CRISPR-based self-cleaving mechanism for controllable gene delivery in human cells
Controllable gene delivery via vector-based systems remains a formidable challenge in mammalian synthetic biology and a desirable asset in gene therapy applications. Here, we introduce a methodology to control the copies and residence time of a gene product delivered in host human cells but also sel...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333380/ https://ncbi.nlm.nih.gov/pubmed/25527740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1326 |
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