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β-Catenin Signaling Drives Differentiation and Proinflammatory Function of IRF8-Dependent Dendritic Cells
β-catenin signaling has recently been tied to the emergence of tolerogenic dendritic cells (DC). Here we demonstrate a novel role for β-catenin in directing DC subset development through IRF8 activation. We found that splenic DC precursors express β-catenin, and DC from mice with CD11c-specific cons...
Tallennettuna:
| Julkaisussa: | J Immunol |
|---|---|
| Päätekijät: | , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333072/ https://ncbi.nlm.nih.gov/pubmed/25416805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402453 |
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