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Differential and overlapping immune programs regulated by IRF3 and IRF5 in plasmacytoid dendritic cells

We examined the signaling pathways and cell type-specific responses of interferon regulatory factor (IRF)5, an immune-regulatory transcription factor. We show that the protein kinases IKKα, IKKβ, IKKε and TBK1 each confer IRF5 phosphorylation/dimerization, thus extending the family of IRF5 activator...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Chow, Kwan T., Wilkins, Courtney, Narita, Miwako, Green, Richard, Knoll, Megan, Loo, Yueh-Ming, Gale, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219909/
https://ncbi.nlm.nih.gov/pubmed/30297339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800221
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