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Differential and overlapping immune programs regulated by IRF3 and IRF5 in plasmacytoid dendritic cells
We examined the signaling pathways and cell type-specific responses of interferon regulatory factor (IRF)5, an immune-regulatory transcription factor. We show that the protein kinases IKKα, IKKβ, IKKε and TBK1 each confer IRF5 phosphorylation/dimerization, thus extending the family of IRF5 activator...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6219909/ https://ncbi.nlm.nih.gov/pubmed/30297339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800221 |
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