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Immune signaling by RIG-I-like receptors
The RIG-I-like receptors (RLRs) RIG-I, MDA5, and LGP2 play a major role in pathogen sensing of RNA virus infection to initiate and modulate antiviral immunity. The RLRs detect viral RNA ligands or processed self RNA in the cytoplasm to triggers innate immunity and inflammation and to impart gene exp...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177755/ https://ncbi.nlm.nih.gov/pubmed/21616437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.05.003 |
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