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Immune signaling by RIG-I-like receptors

The RIG-I-like receptors (RLRs) RIG-I, MDA5, and LGP2 play a major role in pathogen sensing of RNA virus infection to initiate and modulate antiviral immunity. The RLRs detect viral RNA ligands or processed self RNA in the cytoplasm to triggers innate immunity and inflammation and to impart gene exp...

詳細記述

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書誌詳細
主要な著者: Loo, Yueh-Ming, Gale, Michael
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177755/
https://ncbi.nlm.nih.gov/pubmed/21616437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.05.003
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