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Differential recognition of double-stranded RNA by RIG-I–like receptors in antiviral immunity
Retinoic acid–inducible gene (RIG)-I–like receptors (RLRs) are cytosolic RNA helicases that sense viral RNA and trigger signaling pathways that induce the production of type I interferons (IFNs) and proinflammatory cytokines. RLRs recognize distinct and overlapping sets of viruses, but the mechanism...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442628/ https://ncbi.nlm.nih.gov/pubmed/18591413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081210 |
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