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Innate immunity induced by composition-dependent RIG-I recognition of Hepatitis C virus RNA

Innate immune defenses are essential for the control of virus infection and are triggered through host recognition of viral macromolecular motifs known as pathogen-associated molecular patterns (PAMPs) 1. Hepatitis C virus (HCV) is an RNA virus that replicates in the liver, and infects 200 million p...

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Detalhes bibliográficos
Main Authors: Saito, Takeshi, Owen, David M., Jiang, Fuguo, Marcotrigiano, Joseph, Gale, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856441/
https://ncbi.nlm.nih.gov/pubmed/18548002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07106
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