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Structural Basis of RNA Recognition and Activation by Innate Immune Receptor RIG-I
RIG-I (Retinoic acid Inducible Gene - I) is a cytoplasmic pathogen recognition receptor that recognizes pathogen-associated molecular pattern (PAMP) motifs to differentiate between viral and cellular RNAs. RIG-I is activated by blunt-ended double-stranded (ds) RNA with or without a 5′-triphosphate (...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3430514/ https://ncbi.nlm.nih.gov/pubmed/21947008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10537 |
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