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The RIG-I-like Receptor LGP2 Recognizes the Termini of Double-stranded RNA
The RIG-I-like receptors (RLRs), RIG-I and MDA5, recognize single-stranded RNA with 5′ triphosphates and double-stranded RNA (dsRNA) to initiate innate antiviral immune responses. LGP2, a homolog of RIG-I and MDA5 that lacks signaling capability, regulates the signaling of the RLRs. To establish the...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679488/ https://ncbi.nlm.nih.gov/pubmed/19278996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900818200 |
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