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RIG-I Like Receptors in Antiviral Immunity and Therapeutic Applications

The RNA helicase family of RIG-I-like receptors (RLRs) is a key component of host defense mechanisms responsible for detecting viruses and triggering innate immune signaling cascades to control viral replication and dissemination. As cytoplasm-based sensors, RLRs recognize foreign RNA in the cell an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ireton, Reneé C., Gale, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Diversity Preservation International (MDPI) 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185779/
https://ncbi.nlm.nih.gov/pubmed/21994761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v3060906
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