NFATC3 promotes IRF7 transcriptional activity in plasmacy­­toid dendritic cells

Plasmacytoid dendritic cells (pDCs) rapidly produce large amounts of type 1 interferon (IFN) after Toll-like receptor 7 and 9 engagements. This specialized function of type 1 IFN production is directly linked to the constitutive expression of IRF7, the master transcription factor for type 1 IFN prod...

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Vydáno v:J Exp Med
Hlavní autoři: Bao, Musheng, Wang, York, Liu, Ying, Shi, Peiqing, Lu, Hongbo, Sha, Wenwen, Weng, Leiyun, Hanabuchi, Shino, Qin, Jun, Plumas, Joel, Chaperot, Laurence, Zhang, Zhiqiang, Liu, Yong-Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068237/
https://ncbi.nlm.nih.gov/pubmed/27697837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160438
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