Phospholipid Scramblase 1 regulates Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells

Toll-like receptor 9 (TLR9) senses microbial DNA in the endosomes of plasmacytoid dendritic cells (pDCs) and triggers MyD88-dependent type I interferon (IFN) responses. To better understand TLR9 biology in pDCs, we established a yeast two-hybrid library for the identification of TLR9-interacting pro...

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Dettagli Bibliografici
Autori principali: Talukder, Amjad H, Bao, Musheng, Kim, Tae Whan, Facchinetti, Valeria, Hanabuchi, Shino, Bover, Laura, Zal, Tomasz, Liu, Yong-Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391020/
https://ncbi.nlm.nih.gov/pubmed/22453241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.45
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