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NFATC3 promotes IRF7 transcriptional activity in plasmacytoid dendritic cells
Plasmacytoid dendritic cells (pDCs) rapidly produce large amounts of type 1 interferon (IFN) after Toll-like receptor 7 and 9 engagements. This specialized function of type 1 IFN production is directly linked to the constitutive expression of IRF7, the master transcription factor for type 1 IFN prod...
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| 發表在: | J Exp Med |
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| Main Authors: | , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068237/ https://ncbi.nlm.nih.gov/pubmed/27697837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160438 |
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