Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation

Atopic asthma is an inflammatory pulmonary disease associated with Th2 adaptive immune responses triggered by innocuous antigens. While dendritic cells (DCs) are known to shape the adaptive immune response, the mechanisms by which DCs promote Th2 differentiation remain elusive. Herein we demonstrate...

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Autori principali: Williams, Jesse W., Tjota, Melissa Y., Clay, Bryan S., Lugt, Bryan Vander, Bandukwala, Hozefa S., Hrusch, Cara L., Decker, Donna C., Blaine, Kelly M., Fixsen, Bethany R., Singh, Harinder, Sciammas, Roger, Sperling, Anne I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003872/
https://ncbi.nlm.nih.gov/pubmed/24356538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3990
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